The Human Brain Research Laboratory (HBRL) is centered in and administered by the Department of Neurosurgery at the University of Iowa Roy J. and Lucille A. Carver College of Medicine. The HBRL is also part of the University of Iowa General Clinical Research Unit, University of Iowa Institute for Clinical and Translational Science, and is directed by Matthew A. Howard III MD, John C. VanGilder Professor and Head of the Department of Neurosurgery.

The overall aim of research in the HBRL is to gain new knowledge on the neural mechanisms in the human brain underlying sensory, perceptual and cognitive processes related to hearing, speech, language and emotional behavior. The research is carried out by a multi-disciplinary team of research scientists from the University of Iowa as well as from a number of other academic research institutions around the world.